Alzheimer's Disease

Brooks, Megan (2011), Cognitive Tests Beat Biomarkers for Predicting AD, Medscape Medical News

Review of Terry E. Goldberg et. al. in Archives of General Psychology


In a medical record review, changes in cognitive function outperformed biomarkers for predicting conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD).

Reached for comment, Marilyn Albert, MD, from Johns Hopkins University School of Medicine, Baltimore, Maryland, said, "The results are not that surprising, in the sense that it is challenging to predict who is going to progress among those who are mildly impaired."

It's not as if the biological markers aren't important," Dr. Albert said, "but you can gain so much more accuracy if you have the cognitive measures and the functional measures in addition.

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